Postdoctoral Researcher
Company Name:
Oregon Health & Science University
Job Title
Postdoctoral Researcher
Department
Biochemistry & Molecular Biology
Location
RJH 7385
Work Unit Description
Work Schedule, Hours, FTE, Salary Range
FTE: 1.0
Salary range: Commensurate with experience
Location: OHSU Marquam Hill, Portland, OR
Functions/Duties of Position
A position is available in the Department of Biochemistry & Molecular Biology to examine mechanisms of polytopic membrane protein biogenesis, folding, quality control and degradation. Projects involve studies of CFTR, the causative defect in cystic fibrosis, and aquaporin water channels that play a role in renal, CNS and systemic disorders. Experimental systems include cell free protein expression to incorporate non-native amino acids that serve as probes for investigating nascent polypeptide folding and structure. In vitro synthesized proteins are then characterized by biochemical and biophysical approaches to define how ER translocation/chaperone machinery facilitates protein movement across, and integration into, the lipid bilayer during early stages of cotranslational folding. Long-term goals are to identify specific biogenesis events that are disrupted by disease-related mutations, and their mechanisms of correction by small molecules identified in high throughput screens. The position is for a minimum of two years with potential for extension through independent funding opportunities.
Job Requirements
Doctorate degree (Ph.D. and/or MD)
A strong background cell biology, protein biochemistry and molecular biology
Experience in biophysics/fluorescence spectroscopy is encouraged
Additional Details
OHSU is an equal opportunity, affirmative action institution. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of disability or protected veteran status. Applicants with disabilities can request reasonable accommodation by contacting the Affirmative Action and Equal Opportunity Department at .
How To Apply
Apply here online. Be sure to upload a cover letter, CV/resume and three professional references.
Referral Bonus Eligible
Referral Bonus Amount
Drug Testable
NoEstimated Salary: $20 to $28 per hour based on qualifications.
Oregon Health & Science University
Job Title
Postdoctoral Researcher
Department
Biochemistry & Molecular Biology
Location
RJH 7385
Work Unit Description
Work Schedule, Hours, FTE, Salary Range
FTE: 1.0
Salary range: Commensurate with experience
Location: OHSU Marquam Hill, Portland, OR
Functions/Duties of Position
A position is available in the Department of Biochemistry & Molecular Biology to examine mechanisms of polytopic membrane protein biogenesis, folding, quality control and degradation. Projects involve studies of CFTR, the causative defect in cystic fibrosis, and aquaporin water channels that play a role in renal, CNS and systemic disorders. Experimental systems include cell free protein expression to incorporate non-native amino acids that serve as probes for investigating nascent polypeptide folding and structure. In vitro synthesized proteins are then characterized by biochemical and biophysical approaches to define how ER translocation/chaperone machinery facilitates protein movement across, and integration into, the lipid bilayer during early stages of cotranslational folding. Long-term goals are to identify specific biogenesis events that are disrupted by disease-related mutations, and their mechanisms of correction by small molecules identified in high throughput screens. The position is for a minimum of two years with potential for extension through independent funding opportunities.
Job Requirements
Doctorate degree (Ph.D. and/or MD)
A strong background cell biology, protein biochemistry and molecular biology
Experience in biophysics/fluorescence spectroscopy is encouraged
Additional Details
OHSU is an equal opportunity, affirmative action institution. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of disability or protected veteran status. Applicants with disabilities can request reasonable accommodation by contacting the Affirmative Action and Equal Opportunity Department at .
How To Apply
Apply here online. Be sure to upload a cover letter, CV/resume and three professional references.
Referral Bonus Eligible
Referral Bonus Amount
Drug Testable
NoEstimated Salary: $20 to $28 per hour based on qualifications.
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